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The world's most dynamic immune performance supplement. To reinforce your natural resistance to illness, injury and infection. Day-to-day, season-to-season.*

  • Restores frontline defenses & supports long-range immune function.*
  • Activates & enhances 5 immune cell types in 1 daily capsule.*
  • Featuring LC-Plasma (IMMUSE™) probiotic backed by 7 clinical trials.*
Upgrade Yourself®with Performance Lab® PL-Immune™

Broad-range immune support for complex immune challenges

Immune challenges can be unpredictable.

And our defenses sometimes weaken due to vitamin & mineral shortfalls, stress, toxins, and overtraining.

Performance Lab® PL-Immune™ is one supplement designed to help with all these immune concerns.

PL-Immune™ restores weakened defenses first. Then, it activates immune cells, helping them to coordinate, multiply and perform.

From day to day and season to season, PL-Immune™ supplies broad-range support.

Helping your healthy immune system to fight, adapt & evolve to best defend you.

How to take

Upgrade your natural immune response with just 1 daily capsule. Take with your first meal of the day - ideally with a source of dietary fat to help absorption. Use consistently to support your body's immune performance across all activities and all seasons.

Ultramodern Design

PL-Immune™ is a breakthrough immunity formula in convenient capsule form. A dynamic probiotic and antioxidant stack that activates multiple types of immune cells. Restoring fast, frontline defenses and supporting your natural immune function for robust long-range health.

Easy to swallow

Easy to swallow

PL-Immune™ is delivered in convenient, easy-to-swallow 0-sized NutriCaps®. 100% plant-based capsules made from pullulan (fermented tapioca) that are ultraclean and naturally prebiotic-infused. For comfortable digestion and superior nutrient uptake in your body.

Designed for Performance

  • Unique probiotic LC-Plasma (IMMUSE™) activates 5 types of immune cells*
  • Fortifies first-line immune defenses and long-range immune responses*
  • Formulated to help increase the number & activity of immune cells*
  • Replenishes antioxidants for immune system offense & defense*
  • Maintains work productivity & performance via overall immune wellness*
  • Helps fight immune challenges & fatigue associated with exercise*

Healthy for Daily Use

  • LC-Plasma (IMMUSE™) is backed by 7 human clinical trials for safety and efficacy*
  • Supports your healthy days from season to season with natural nutrition*
  • Restores foundational immune support: NutriGenesis® Vitamin D, Vitamin C, Zinc & Selenium
  • 100% plant-based, prebiotic-infused NutriCaps® from pullulan (fermented tapioca)


Nutrition Facts

Serving Size: 1 NutriCap®

Servings per container: 30

Per NutriCap®
Vitamin D (via NutriGenesis®) 25 mcg 125
Vitamin C (via NutriGenesis®) 30 mg 33
Selenium (via NutriGenesis®) 25 mcg 45
Zinc (via NutriGenesis®) 5 mg 45
Lactococcus lactis strain Plasma (IMMUSE™ - Paraprobiotic*) 50 mg
Setria® Glutathione 250 mg
Daily Values are based on a 2,000 calories per day diet.
† NRV N/A.

Other Ingredients: NutriCaps® Pullulan Capsule, NuFlow® Rice Concentrate.

Suitable for vegans. Contains NO soy, egg, fish, shellfish, dairy, peanut, tree nuts, wheat, or other allergens. Non-GMO and non-irradiated. Free of gluten, synthetic additives, artificial colors and preservatives.

NutriGenesis® and NutriCaps® are registered trademarks of XGen Biotech Ltd. Setria® is a registered trademark of Kyowa Hakko Bio Co., Ltd.

BPA Free. Please Recycle.

Copyright © Performance Lab Ltd. All rights reserved.

The Science

NOW: One immune formula for many immune concerns

PL-Immune™ does more than typical immune supplements, delivering true broad-range support.

PL-Immune™ restores & maintains immune-critical essentials

PL-Immune Vitmains & Minerals

Vitamins & Minerals

Most important nutrients for healthy immune system function, but many people fail to get enough

PL-Immune Vitmains & Minerals


Used by the immune system to destroy invaders while limiting collateral damage to healthy cells

PL-Immune™ activates 5 types of immune cells

PL-Immune pDC

pDC (Plasmacytoid dendritic cells)

The Commander: Activates 4 immune cell classes to fight

Natural Killer (NK) Cells

Fast, non-specific defense; Target & kill all invaders plus infected cells


Seek and destroy specific invaders, infected cells & damaged cells


Direct B-cells and T-cells to make antibodies and fight invaders

B-Cells (B lymphocytes)

Produce antibodies that target, bind & neutralize specific antigens

PL-Immune™ helps short-range & long-range immune function

Innate Immune System
(short-range defenses)

  • Immediate first line defense
  • Non-specific; identifies & attacks all invaders
  • Includes skin, mucus membrane & gut barriers
  • Helps keep invaders out of the bloodstream

Adaptive Immune System
(long-range defenses)

  • Stronger but slower-acting "second line" defense
  • Specific: Remembers, recognizes & attacks invaders
  • Enables immune system to fight seasonal challenges
  • Help your defenses evolved & adapt for the future
PL-Immune Delivers Broad Range Support

PL-Immune™ delivers true broad-range support

From day to day and season to season, PL-Immune™ helps your system fight a variety of challenges, old and new.

LC-Plasma (IMMUSE™), 50 mg

PL-Immune™ features heat-treated probiotic LC-Plasma (Lactococcus lactis) as ultramodern IMMUSE™.

Typical lactic acid probiotics, such as those found in yogurt, support immune system health by activating one class of immune cells: Natural Killer (NK) cells.

LC-Plasma is a breakthrough probiotic for immune function because it activates pDC (plasmacytoid dendritic cells): The commanders of the immune system.

By stimulating pDC, PL-Immune™ LC-Plasma can activate 4 different types of immune cells — priming both the innate and adaptive immune systems for more dynamic and robust responses.

PL-Immune Conventional Lactic Acid
PL-Immune Immuse

Out of hundreds of beneficial bacteria studied, only one was shown to stimulate the pDC that activates the immune system: LC-Plasma, found in PL-Immune™.

Researchers in human clinical trials have suggested LC-Plasma may help to:

  • Maintain healthy immune system function against seasonal challenges*
  • Promote overall immune wellness for work productivity and performance*
  • Fight immune challenges and fatigue associated with high-intensity training*

PL-Immune™ supplies LC-Plasma as IMMUSE™, a patented form studied in 7 clinical trials for efficacy and 2 clinical trials for safety. Each PL-Immune™ serving supplies 100 billion LC-Plasma cells.

Setria® Glutathione, 250 mg

Glutathione is an organic protein that some researchers have suggested may be the single most important antioxidant in human health. Glutathione may support healthy immune function with:

PL-Immune Antixoidants

1. Antioxidant Support

Healthy immune system function relies on antioxidants, which play a role in immune cell activation, immune responses, and protection of healthy cells and immune cells.

Glutathione is considered a powerful antioxidant for supporting the immune system.

Glutathione is also considered a Master Antioxidant because it recharges other antioxidants — including PL-Immune™ NutriGenesis® Vitamin C — and extends their immune-supportive, cell-protective activities.

PL-Immune Antioxidants

2. Immune Cell Support

Glutathione promotes the formation, multiplication and function of some immune cells. Researchers have suggested healthy Glutathione levels may:

  • Increase numbers of T-cells (white blood cells) and support their healthy function
  • Stimulate production and activity of immune system's natural killer (NK) cells
  • Support immune cells' normal antibody responses
PL-Immune Antioxidants

3. Gut Barrier Support

The gut lining is a crucial immune barrier that helps keep invaders out of the bloodstream.

Glutathione helps maintain gut lining integrity. In addition, glutathione is suggested to intercept and neutralize toxins in the GI tract before they are absorbed.

PL-Immune™ Setria® Glutathione is the only glutathione clinically shown to both raise glutathione levels in the bloodstream and support your immune system. Setria® Glutathione is also premium-quality, made with patented fermentation that yields a purified, non-GMO, vegetarian and allergen-free finished product.

PL-Immune™ for Athletes' Immune Support

Exercising to stay healthy? You should know that intense training can suppress immune function. Not to mention those nasty pathogens you might encounter in the gym and locker room.

PL-Immune™ maintains your defenses as you train: LC-Plasma (IMMUSE™) + Setria® Glutathione have been shown in research to help ward off exercise-induced immune challenges and fatigue.

NutriGenesis® Immune Essentials

  • Vitamin D, 1000 IU
  • Zinc, 5 mg
  • Vitamin C, 30 mg
  • Selenium, 25 mcg

Low levels of certain essential vitamins and minerals can weaken immune system function.

That's why PL-Immune™ includes essential reinforcements for your immune defenses, as high-absorption NutriGenesis® Vitamin D, Vitamin C, Zinc and Selenium.

NutriGenesis® Vitamin D, 1000 IU

NutriGenesis® Vitamin D helps restore the healthy levels you need to support both innate and adaptive immune responses:

  • Innate: Vitamin D is most strongly associated with the innate immune system. It is known for its potential to fight bacteria: Vitamin D may enhance the antimicrobial effects of immune cells.
  • Adaptive: Vitamin D helps to limit the proliferation of certain immune cells. This bioactivity may help promote more balanced immune responses – not too much, nor too little.

NutriGenesis® Vitamin C, 30 mg

Vitamin C supports many aspects of healthy immune function, including:

  • Immune cells: Enhances development and proliferation of B-cells and T-cells
  • Immune responses: Activates and sustains immune system’s protective activity
  • Exercise challenges: Bolsters immune responses during physical stress like exercise
  • Barrier integrity: Strengthens skin & gut barrier functions against invaders
  • Antioxidant support: Legendary reputation for robust immune defenses

Vitamin C deficiency is rare, but in times of immune challenges many people up their intake.

NutriGenesis® Zinc, 5 mg

Low zinc, a common concern, suppresses the immune system and skews immune cell activity.

Supplementing with zinc helps restore immune cells’ healthy function, including:

  • NK cells: Supplementing with zinc has been suggested to help improve NK cell activity.
  • T-Cells: Zinc enables these immune cells to grow, activate & function properly

Zinc also contributes to antioxidant activity that helps to protect immune cells and support your natural defenses across both innate and adaptive responses.

NutriGenesis® Selenium, 25 mcg

Selenium is essential for healthy immune function. It strengthens natural defenses in two ways:

  • Selenium helps form glutathione. Selenium’s glutathione support teams up with PL-Immune™ L-Glutathione. Result: 2X immune-defending super-antioxidant activity
  • Selenium regulates immune cell activity. Selenium forms selenoproteins that are required for healthy production, function and activity of immune T-cells and NK cells

Researchers report up to 1 billion people worldwide may have selenium deficiency. PL-Immune™ includes selenium to help restore ideal levels required for robust immune system performance.

PL-Immune Vitamins and Minerals

Performance Lab® NutriGenesis® vitamins and minerals are a nutrition technology breakthrough: They include natural cofactors that enhance absorption, bioavailability and immune-supportive activity.

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Performance Lab® PL-Immune™

Ready to upgrade your immune support? Take Performance Lab® PL-Immune™ to reinforce your nature defenses against illness and infection.

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+ 1 Box FREE (4 Boxes)


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Who should take Performance Lab® PL-Immune™?

PL-Immune™ can be taken by anyone seeking to support healthy immune system function.

How do I take Performance Lab® PL-Immune™?

For best results take 1 capsule daily.

Is Performance Lab® PL-Immune™ safe?

Like all Performance Lab® supplements, PL-Immune™ is designed to be safe for long-term daily use, without the need for cycling. PL-Immune™ achieves this by using pure, potent ingredients that are dosed appropriately and in line with clinical research. PL-Immune™'s clean formula design – free of GMOs, gluten, soy, colorants, preservatives and other additives – is also well-tolerated by the body, and safe for long-term use.

What is NutriGenesis®?

NutriGenesis® is a Performance Lab® nutrition technology innovation: Vitamins, minerals and amino acids grown in live cultures at our state-of-the-art lab.

A true biological nutrient form, NutriGenesis® closely mirrors the molecular structure of food nutrients. NutriGenesis® nutrients offer significant advantages over standard nutrient forms.

Featured in several Performance Lab® formulas, NutriGenesis® vitamins, minerals and amino acids are bioengineered to be safe, active and highly effective for overall health and performance.

Why did Performance Lab® develop NutriGenesis®?

Vitamins, minerals and amino acids are the most important nutrients you need to build a strong foundation for health and performance.

Performance Lab® developed NutriGenesis® to have our own in-house vitamins, minerals and amino acids to use in our own nutritional supplements.

In producing NutriGenesis®, Performance Lab® can best maintain our industry-leading quality standards for cleanliness, purity, effectiveness and eco-friendliness, across all our ultramodern formulas.

How is NutriGenesis® different from other nutrient forms?

Not all vitamins, minerals and amino acids are the same. There are many nutrient forms, produced with a variety of processes. Some of the most popular nutrient forms available in supplements today include:

Whole Food Concentrates

Whole food vitamin and mineral supplements are sourced from fruits, vegetables, herbs and mushrooms. They include natural cofactors that make food nutrients so easy for the body to absorb and utilize. However, they do require extensive processing and may be made with GMOs, mass agriculture and dirty eco-destructive practices.

Isolated Chemical (USP) Nutrients

Isolated Chemical (USP) is the cheapest vitamin and mineral form found in the most basic multivitamin supplements. This synthetic form chemically alters vitamins and minerals, isolating them from their whole-food cofactors. As a result, Isolated Chemical (USP) nutrients are typically harder to absorb and less effective than whole food nutrients.

Chelated Minerals

In this process, a mineral nutrient (such as iron, calcium, zinc) is bound with a chelator: An organic molecule (often an amino acid) that is large enough to enrobe the mineral. By surrounding the mineral, the chelator protects it against degradation. Chelated nutrients are highly stable and may improve nutrient uptake and utilization.

NutriGenesis® is different from traditional nutrient forms: Bioengineered to be better.

NutriGenesis® are cultured nutrients that replicate the creation of vitamins, minerals and aminos in nature.

NutriGenesis® is based on the work of Nobel Prize-winning physiologist Albert Szent Gyorgy, who theorized that nutrients presented in their naturally grown forms supply cofactors that make them more bioavailable, biologically active and effective than nutrients that are isolated.

In the NutriGenesis® process, single-cell organisms are seeded with micronutrients in a hydroponic growth medium.

The live single-cell organisms “eat” the micronutrients, divide and thrive. As the cultures grow, they produce fresh new NutriGenesis® vitamins, minerals and aminos within a matrix of natural cofactors. This familiar structure is more easily absorbed and utilized by the body.

More on the NutriGenesis® Process

NutriGenesis® advantages over other forms:

NutriGenesis® is essentially food nutrition. Mirroring food nutrients molecule-by-molecule, our vitamins, minerals and aminos are presented in pure elemental form. Maximum nutrition: Nothing more, nothing less.

Enhanced effectiveness. Because NutriGenesis® nutrients are in food-matrix form, they are recognized by the body as nature-identical -- maximizing nutrient uptake, bioavailability and beneficial activity.

Patented and researched. The patented process behind NutriGenesis® has been shown in research to enhance nutrient absorption and retention (when compared to chemical isolates).

Cleaner and safer. NutriGenesis® is produced in a sterile, tightly controlled lab setting. NutriGenesis® is minimally processed, requiring no pesticides, herbicides or other synthetics associated with some other whole-food nutrients.

Better for the planet: The NutriGenesis® process is clean and efficient, with little carbon footprint or environmental impact – especially when compared to factory farming for phytonutrients and strip mining for minerals.

Which formulas feature NutriGenesis® nutrients?

It all begins with NutriGenesis® Multi for Men and Multi for Women: Performance Lab®’s multivitamin starting point for human performance optimization.

NutriGenesis® vitamins, minerals and amino acids are also found in Performance Lab® formulas Stim, Flex, BCAA, Pre, Post and Maintain.

Beyond Performance Lab®, NutriGenesis® B-Vitamins are found in Mind Lab Pro®: the Universal Nootropic™.

30-Day Performance Promise

Your first order of any Performance Lab® product is covered by our 30-day performance promise.

Put Performance Lab® PL-Immune™ to the test for a full 30 days and if you don’t see results, we’ll refund your money. No questions asked.

Simply get in touch with a member of our Customer Care team.

The Performance Lab® Performance Promise covers one container of any of our products, up to a maximum of three products per order. You’ll need to return any unused boxes.

PL-Immune™ stacks well with…

PL-Immune™ and NutriGenesis® Multi for Men

NutriGenesis® Multi augments PL-Immune™'s NutriGenesis® Vitamin C, Vitamin D, Zinc and Selenium while adding extra immune essentials including Vitamin E, B-Vitamins, Vitamin A, Copper and Iron.

Together, PL-Immune™ + NutriGenesis® Multi build and strengthen your essential nutrient base for immune system health and overall wellness.

Learn More
NutriGenesis® Multi for Men

PL-Immune™ and Prebiotic

Prebiotic nourishes gut Bifidobacterium probiotics that support healthy barrier immune functions. Prebiotic also helps with absorption and natural synthesis of some vitamins and minerals for immunity.

Together, Prebiotic + PL-Immune™ supply dynamic immune activity in the form of natural support for tried and true Bifidobacterium and directly supplying the emerging immune paraprobiotic Lactococcus lactis.

Learn More

PL-Immune™ and Omega-3

Performance Lab® Omega-3 fatty acids DHA+EPA help to regulate the immune system and promote balanced immune responses. DHA+EPA also benefit the microbiome, which supports immune health.

PL-Immune™ + Omega-3 combine together to activate and enhance the immune system while helping to keep immune responses in a balanced and healthy range.

Learn More
Omega 3


The research and studies behind Performance Lab® PL-Immune™.

Learn More


Jounai K, Ikado K, Sugimura T, Ano Y, Braun J, et al. (2012) Spherical Lactic Acid Bacteria Activate Plasmacytoid Dendritic Cells Immunomodulatory Function via TLR9-Dependent Crosstalk with Myeloid Dendritic Cells. PLOS ONE 7(4): e32588. https://doi.org/10.1371/journal.pone.0032588
Sugimura, T., Takahashi, H., Jounai, K., Ohshio, K., Kanayama, M., Tazumi, K., . . . Yamamoto, N. (2015). Effects of oral intake of plasmacytoid dendritic cells-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus. British Journal of Nutrition, 114(5), 727-733. doi:10.1017/S0007114515002408
Kokubo T, Komano Y, Tsuji R, Fujiwara D, Fujii T, Kanauchi O. The Effects of Plasmacytoid Dendritic Cell-Stimulative Lactic Acid Bacteria, Lactococcus lactis Strain Plasma, on Exercise-Induced Fatigue and Recovery via Immunomodulatory Action. Int J Sport Nutr Exerc Metab. 2019;29(4):354–358. Published 2019 Jul 1. doi:10.1123/ijsnem.2018-0377
Sugimura, T., Takahashi, H., Jounai, K., Ohshio, K., Kanayama, M., Tazumi, K., . . . Yamamoto, N. (2015). Effects of oral intake of plasmacytoid dendritic cells-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus. British Journal of Nutrition, 114(5), 727-733. doi:10.1017/S0007114515002408
Fujii T, Tomita Y, Ikushima S, Horie A, Fujiwara D. Draft Genome Sequence of Lactococcus lactis subsp. lactis JCM 5805T, a Strain That Induces Plasmacytoid Dendritic Cell Activation. Genome Announc. 2015;3(2):e00113-15. Published 2015 Mar 19. doi:10.1128/genomeA.00113-15
Hiroaki Suzuki, Konomi Ohshio & Daisuke Fujiwara (2016) Lactococcus lactis subsp. lactis JCM 5805 activates natural killer cells via dendritic cells, Bioscience, Biotechnology, and Biochemistry, 80:4, 798-800, DOI: 10.1080/09168451.2015.1116922


Richie JP Jr, Nichenametla S, Neidig W, et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015;54(2):251-263. doi:10.1007/s00394-014-0706-z
Knight JA. Review: Free radicals, antioxidants, and the immune system. Ann Clin Lab Sci. 2000;30(2):145-158.
Dröge W, Breitkreutz R. Glutathione and immune function. Proc Nutr Soc. 2000;59(4):595-600. doi:10.1017/s0029665100000847
Bendich A. Physiological role of antioxidants in the immune system. J Dairy Sci. 1993 Sep;76(9):2789-94.

NutriGenesis® Immune Essentials

Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch. Intern. Med. 2009;169(4):384–390.
Bendich A. Physiological role of antioxidants in the immune system. J Dairy Sci. 1993;76(9):2789-2794.
Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017;9(11):1211. Published 2017 Nov 3. doi:10.3390/nu9111211
Bonaventura P, Benedetti G, Albarède F, Miossec P. Zinc and its role in immunity and inflammation. Autoimmun Rev. 2015;14(4):277-285.
Brown KM, Arthur JR. Selenium, selenoproteins and human health: a review. Public Health Nutr. 2001 Apr;4(2B):593-9. doi: 10.1079/phn2001143. PMID: 11683552.
Navarro-Alarcon M, Cabrera-Vique C. Selenium in food and the human body: a review. Sci Total Environ. 2008 Aug 1;400(1-3):115-41. doi: 10.1016/j.scitotenv.2008.06.024. Epub 2008 Jul 26. PMID: 18657851.
Shreenath AP, Ameer MA, Dooley J. Selenium Deficiency. (Updated 2020 Aug 24). In: StatPearls Internet. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.

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